The vestibular end-organs play in motion, equilibrium, and spatial recognition. Keeping a balance is maintained by the brain’s output from a complex set of sensorimotor control systems inputs, which are visual, muscles, joints, and the vestibular end-organs. Movements and balance are controlled by sensorimotor systems as sensory peripheral organs such as vision, tactile, and the vestibular end-organs. This imaging technique will contribute to our understanding of pathology and calcium metabolism in the in vivo vestibulum. These created 3D microanatomical images can allow detailed observations of changes in physiological and biological information. The saccule, utricle, and endolymphatic sac were not constantly shaped according to their conditions. In benign paroxysmal positional vertigo (BPPV), the otolith increased in the utricular macula but did not change much in the saccular macula. In Meniere’s disease (MD), the saccular macula was larger and the utricular macula was smaller. Both shapes and volumes were not always constant depending on time. The changes in the amount of CaCO 3 in the maculae and the endolymphatic sac showed various morphologies, reflecting the balance status of each subject. The saccular macula was almost bud-shaped. The utricular macula was elongated pea-shaped. The otolith and otolith organs images were reconstructed from a texture synthesis algorithm under the skull volume rendering algorithm using a cutting-plane method. We will create the technique for 3D microanatomical images of them, and investigate the in vivo internal state and metabolisms. Although the otolith and otolith organs correlate with vertigo and instability, there is no method to investigate them without harmful procedures.

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